Payroll Manager

Company Overview
Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.
Opportunity Overview
Rhythm Pharmaceuticals is seeking a hands-on, detail-oriented Payroll Manager to join our Finance team. In this role, you will be directly involved in overseeing and processing US and Canada payroll operations. The ideal candidate will have experience with ADP Workforce Now and a strong understanding of payroll compliance with federal, state, and local tax laws and regulations. This position is based in Boston and follows a hybrid work model to promote collaboration and flexibility.
Responsibilities and Duties

• Manage and process regular bi-weekly payrolls using ADP Workforce Now.
• Process off-cycle bonus and equity payrolls.
• Ensure payroll compliance with federal, state, and local payroll laws and regulations.
• Oversee payroll tax filings, payments, corrections, and resolve tax issues.
• Register payroll tax accounts in new tax jurisdictions and maintain validation tables in ADP.
• Partner with payroll providers to support payroll configuration updates.
• Adhere to established payroll processes, internal controls, and procedures to ensure accuracy and efficiency.
• Collaborate with HR, Finance, and other departments on payroll-related projects, audits, reporting, and reconciliations.
• Address employee payroll inquiries promptly, professionally, and with a service mindset, providing clear explanations regarding deductions, adjustments, and general payroll issues.
• Investigate and resolve payroll discrepancies, ensuring any errors are corrected quickly and thoroughly.
• Identify opportunities to streamline and improve payroll processing and overall payroll experience for employees.
• Prepare payroll-related reports.
• Manage US quarterly and year-end processes.
• Other ad hoc projects and related tasks as necessary to drive our mission and culture

Qualifications and Skills

• Bachelor’s degree in business, Accounting, or a related field, or equivalent experience.
• At least 5 years of payroll experience, including exposure to multi-state payroll.
• ADP Workforce Now experience preferred.
• Strong knowledge of U.S. payroll laws and regulations.
• Highly proficient in Excel and a strong eye for detail.
• Excellent problem-solving skills and ability to manage competing priorities.
• Exceptional communication skills to interact with employees and payroll service providers.
• Ability to handle sensitive and confidential information with discretion.
• Certified Payroll Professional (CPP) certification is a plus.

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs.
More about Rhythm
We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism.
At Rhythm our core values are:

• We are committed to advancing scientific understanding to improve patients’ lives
• We are inspired to tackle tough challenges and have the courage to ask bold questions
• We are eager to learn and adapt
• We believe collaboration and ownership are foundational for our success
• We value the unique contribution each individual brings to furthering our mission

Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law.
Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.