Principal Scientist - Biomarker Assay Development - Translational Research

About the Department
Our Research & Development organization brings together the best minds in life science innovation. The teams located in facilities in Lexington, Watertown, Cambridge and Seattle reflect the full R&D continuum, from early research through late-stage clinical development. Here, we are building for the future, creating a distinct R&D community based on collaboration, partnerships, and cutting-edge research across multiple modalities and therapeutic areas. We recognize that improving human health starts here and that patients rely on us. Our R&D hub merges biotech speed and agility with large pharmaceutical company quality, resources, and stability, uniting the best of both worlds to develop new medicines for patients.
The Position
The Principal Scientist will lead the scientific efforts in developing biomarker assay strategies, qualifying new biomarker assays (LBA, flow cytometry), and introducing innovative technological platforms and methods for biomarker quantification. This will involve serving as a subject matter expert, offering strategic guidance on assays and technology to project teams, and initiating and leading strategic scientific and technological partnerships within the biomarker assay field. Additionally, the Principal Scientist may provide mentorship and training to colleagues at various levels within the Biomarker Assay Development department, and will represent the organization in the external scientific community through impactful research publications and presentations.
Relationship
Reports to the Director Biomarker Assay Development. Internal relationships include working closely with technical staff and other members of the Biomarker Assay Development department (in the US and Denmark); regular collaborations with members of other research departments at GNAT, GDD and GRT; frequent interaction with project managers and other colleagues across global R&D. Individual may indirectly supervise colleagues at various levels.
Individual will interact with external research collaborators both academia- and industry-based
Essential Functions

• Independently handle complex tasks requiring specialized knowledge crucial to biomarker assay development, while understanding the relationship between scientific project objectives and long-term business needs.
• Demonstrates established depth and/or breadth expertise biomarker assays, and be able to provide strong technical guidance within the field of biomarker assay development .
• Leads or supervises multiple biomarker assay strategies concurrently, and is accountable for planning execution, and delivering, including setting strategy goals and timelines.
• Develop, plan, and execute biomarker assay strategies for the development and qualification of assays for TE biomarkers, PoM biomarkers, and disease modulation-associated biomarkers.
• Maintain a comprehensive understanding of theoretical knowledge and stay connected to the external scientific community through ongoing assessment of relevant literature.
• Propose new projects that align with the strategic agenda and address gaps in technological capabilities.
• Actively participate in virtual global team meetings.
• Establish, lead, and maintain professional networks internally and externally, identifying opportunities for academic/industrial collaboration and co-creation
• Serve as the organization's representative by externally communicating impactful scientific research through presentations at external conferences, and by publishing in scientific journals and patents
• Provides significant mentorship and training of junior and senior colleagues.

Qualifications

• Master's degree with 12+ years of relevant experience, or PhD with 8+ years of relevant experience required
• Relevant required experience:
  • Proficiency in scientific immunoassays with a strong track record in conducting biomarker assay establishment and analytical qualification
  • Experience in drug discovery and development within the pharmaceutical industry or similar
  • Demonstrates exceptional verbal and written communication skills, including the ability to create and deliver compelling presentations
• Preferred experience includes:
  • Proficiency in flow cytometry
  • Understanding of pathophysiological mechanisms, particularly in metabolic disease biology and biomarkers
  • Comprehensive understanding of both preclinical research and early clinical development
  • Strong capabilities in cross-functional teamwork and working experience in international matrix organizations

We commit to an inclusive recruitment process and equality of opportunity for all our job applicants.
At Novo Nordisk we recognize that it is no longer good enough to aspire to be the best company in the world. We need to aspire to be the best company for the world and we know that this is only possible with talented employees with diverse perspectives, backgrounds and cultures. We are therefore committed to creating an inclusive culture that celebrates the diversity of our employees, the patients we serve and communities we operate in. Together, we're life changing.
Novo Nordisk is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, ethnicity, color, religion, sex, gender identity, sexual orientation, national origin, disability, protected veteran status or any other characteristic protected by local, state or federal laws, rules or regulations.
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